Asymmetric Direct Vinylogous Aldol Reaction of Unactivated γ-Butenolide to Aldehydes.

DOI Number:

10.1021/jo100946d
Link to literature

Reaction Category:

Aldol | Vinylogous Aldol

RXNO ID:

RXNO_0000016

Educt:

γ-butenolide, aldehydes

Product:

substituted (R)-5-(hydroxymethyl)furan-2(5H)-one

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7