Highly efficient enantioselective synthesis of bispiro [benzofuran-oxindole/benzofuran-chromanone]s through organocatalytic inter-/intramolecular Michael cycloaddition.
DOI Number:
10.1016/j.cclet.2019.06.015
Reaction Category:
Educt:
substituted benzofuranone, 3-((2-oxo-2,3-dihydrobenzofuran-3-yl)methyl)-4H-chromen-4-one, N-protected 3-((4-oxo-4H-chromen-3-yl)methyl)indolin-2-one
Product:
bispiro [benzofuran-oxindole/benzofuran-chromanone]s
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7