Organocatalytic and enantioselective Michael reaction of malonates to 3-nitro-2H-chromenes.

DOI Number:

10.1016/j.catcom.2010.11.014
Link to literature

Reaction Category:

Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

6-chloro-3-nitro-2H-chromene, dimethyl malonate

Product:

dimethyl 2-((3S,4R)-6-chloro-3-nitrochroman-4-yl)malonate

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7