Copper (I)-catalyzed asymmetric reactions involving radicals.

DOI Number:

10.1021/acs.accounts.9b00381
Link to literature

Reaction Category:

Cyclization | Fluorination | Fluoromethylation | Isoxazoline cyclization | Trifluoromethylation

MOP ID:

MOP_0000368

Educt:

(E)-1-(3-bromophenyl)-3-phenylbut-3-en-1-one oxime

Product:

(S)-3-(3-bromophenyl)-5-phenyl-5-(2,2,2-trifluoroethyl)-4,5-dihydroisoxazole

Catalyst:

copper acetate, N-[(9R)-10,11-dihydrocinchonan-9-yl]-2,3,4,5,6-pentamethyl-benzenesulfonamide

Cas No:

2228076-17-1

Associated Product from Buchler GmbH:

Dihydrocinchonine Base

Cas No:

485-65-4