Asymmetric synthesis of 2,3,4-trisubstituted piperidines.

DOI Number:

10.1055/s-0036-1588299
Link to literature

Reaction Category:

Aza-Michael | Cyclization | Cyclization | Further Cyclizations | Michael Addition

MOP ID:

MOP_0000561

Educt:

nitroalkenes, ethyl (E)-5-(benzylamino)pent-2-enoate

Product:

substituted ethyl 2-((3S)-1-benzyl-3-nitropiperidin-4-yl)acetate

Catalyst:

N-[3,5-bis(trifluoromethyl)phenyl]-N′-(9R)-cinchonan-9-yl-thiourea

Cas No:

851477-19-5

Associated Product from Buchler GmbH:

Cinchonine Base

Cas No:

118-10-5