Enantioselective synthesis of trifluoromethyl substituted cyclohexanones via an organocatalytic cascade Michael/aldol reaction.

DOI Number:

10.1039/D0OB00004C
Link to literature

Reaction Category:

Aldol | Aldol | Cascade reaction | Cyclization | Cyclization | Further Cyclizations | Michael | Michael Addition

MOP ID:

MOP_0000561

Educt:

α,β-unsaturated ketones, trifluoro-3-oxobutanoates

Product:

trifluoromethyl substituted cyclohexanones

Catalyst:

(9R)-6′-methoxy-cinchonan-9-amine

Cas No:

287979-82-2

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2