Accessing axially chiral biaryls via organocatalytic enantioselective dynamic-kinetic resolution-semipinacol rearrangement.

DOI Number:

10.1021/acscatal.7b01056
Link to literature

Reaction Category:

Atropisomer synthesis | Dynamic Kinetic Resolution | Resolution

Educt:

4,5-dimethyl-9-(1-phenylvinyl)-9H-fluoren-9-ol, N-bromophthalimide

Product:

(R)-10-(bromomethyl)-4,5-dimethyl-10-phenylphenanthren-9(10H)-one

Catalyst:

(-)-camphorsulfonic acid, 1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7

Associated Product from Buchler GmbH:

1,4-Bis(9-O-dihydroquinidinyl)phthalazine ((DHQD)2PHAL)

Cas No:

140853-10-7