Enantioselective synthesis of chiral carbocyclic pyrimidine nucleosides via asymmetric cyclopropanation.

DOI Number:

10.1016/j.tetlet.2019.151183
Link to literature

Reaction Category:

Cyclopropanation

Educt:

substituted 2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acrylic ester, substituted 2-bromoacetate

Product:

carbocyclic pyrimidine nucleosides

Catalyst:

1,4-Bis[(9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-9,10-anthracenedione

Cas No:

176298-44-5

Associated Product from Buchler GmbH:

Dihydroquinidine Base

Cas No:

1435-55-8