Catalytic Asymmetric Synthesis of Chiral α,α-Dialkyl Aminonitriles via Reaction of Cyanoketimines.

DOI Number:

10.1021/jacs.4c03333
Link to literature

Reaction Category:

Strecker

RXNO ID:

RXNO_0000207

Educt:

N-(4-nitrobenzyl)-3-phenylpropanimidoyl cyanide, (E)-but-2-enal

Product:

α,α-dialkyl aminonitriles

Catalyst:

9-[(6-chloro-2,5-diphenyl-4-pyrimidinyl)oxy]-1-[[2′-(1,1-dimethylethoxy)-3,3′′,4,4′′,5,5′′-hexamethoxy[1,1′:3′,1′′-terphenyl]-5′-yl]methyl]-6′-methoxy-cinchonanium bromide

Cas No:

3037395-53-9

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2