Asymmetric synthesis and antiviral activity of novel chiral amino-pyrimidine derivatives.

DOI Number:

10.1016/j.tetlet.2018.07.020
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

4-methoxy-6-methylpyrimidin-2-amine, malonic acid esters, aldehydes

Product:

amino-pyrimidine derivatives

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0