Asymmetric Mannich reaction: highly enantioselective synthesis of 3-amino-oxindoles via chiral squaramide based H-bond donor catalysis.

DOI Number:

10.1039/C6RA16877A
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

isatin derived N-boc ketimines, 1,3-diketones

Product:

3-amino-oxindoles

Catalyst:

3-[[[3,5-Bis(trifluoromethyl)phenyl]methyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1210360-60-3

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0