Control of Diastereoselectivity in Tandem Asymmetric Reactions Generating Nonadjacent Stereocenters with Bifunctional Catalysis by Cinchona Alkaloids.
DOI Number:
10.1021/ja0670409
Reaction Category:
RXNO ID:
RXNO_0000009
Educt:
1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, 2-chloroacrylonitrile
Product:
(S)-2-((S)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile, (R)-2-((S)-2-chloro-2-cyanoethyl)-1-oxo-2,3-dihydro-1H-indene-2-carbonitrile
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7