A New Class of Squaramide-Containing Phase-Transfer Catalysts: Application to Asymmetric Fluorination of β-Keto Esters.

DOI Number:

10.1055/s-0035-1560645
Link to literature

Reaction Category:

Fluorination | Fluorination of beta-ketoester

MOP ID:

MOP_0000553

Educt:

tert-butyl 1-oxo-2,3-dihydro-1H-indene-2-carboxylates, N-fluoro-N-(phenylsulfonyl)benzenesulfonamide

Product:

tert-butyl (S)-2-fluoro-1-oxo-2,3-dihydro-1H-indene-2-carboxylate

Catalyst:

(1S,2S,4S,5R)-2-((S)-((2-((3,5-bis(trifluoromethyl)phenyl)amino)-3,4-dioxocyclobut-1-en-1-yl)amino)(6-methoxyquinolin-4-yl)methyl)-1-(3,5-di-tert-butylbenzyl)-5-vinylquinuclidin-1-ium bromide

Cas No:

-

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0