Novel chiral thiourea derived from hydroquinine and L-phenylglycinol: an effective catalyst for enantio-and diastereoselective aza-Henry reaction.

DOI Number:

10.1021/acsomega.0c06233

Reaction Category:

RXNO ID:

RXNO_0000235

Educt:

substituted 1-benzyl-3-iminoindolinone, primary nitroalkanes

Product:

substituted (R)-3-amino-1-benzyl-3-((R)-1-nitroethyl)indolin-2-one

Catalyst:

N-[(8α,9S)-10,11-dihydro-6′-methoxycinchonan-9-yl]-N′-[(1S)-1-hydroxy-2-phenylethyl]-thiourea

Cas No:

2618369-44-9

Cas No:

522-66-7