Enantioselective inverse-electron demand Aza-Diels–Alder reaction: ipso, α-selectivity of silyl dienol ethers.
DOI Number:
10.1021/acscatal.1c03390
Reaction Category:
RXNO ID:
RXNO_0000006
Educt:
(E)-(buta-1,3-dien-1-yloxy)trimethylsilanes, substituted (Z)-4-methyl-N-(2-methylenebenzofuran-3(2H)-ylidene)benzenesulfonamide
Product:
substituted (2R,3S)-1-tosyl-3-vinyl-1,2,3,4-tetrahydrobenzofuro[3,2-b]pyridin-2-ol
Catalyst:
3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[(8α,9S)-cinchonan-9-ylamino]-3-Cyclobutene-1,2-dione
Cas No:
1256245-86-9
Associated Product from Buchler GmbH:
Cinchonidine Base
Cas No:
485-71-2