Asymmetric Aza-Mannich Addition of Oxazolones to N-Tosyl Aldimines: Synthesis of Chiral α-Disubstituted α,β-Diamino Acids.

DOI Number:

10.1021/ol902916s
Link to literature

Reaction Category:

Mannich | Mannich

RXNO ID:

RXNO_0000032

Educt:

oxazolones, N-tosyl aldimines

Product:

substituted 4-methyl-N-((5-oxo-4,5-dihydrooxazol-4-yl)methyl)benzenesulfonamide

Catalyst:

(8α,9R)-6′-Methoxy-9-[(trimethylsilyl)oxy]cinchonan

Cas No:

75332-25-1

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0