Squaramide-catalyzed enantioselective Michael addition of nitromethane to 2-enoylazaarenes: synthesis of chiral azaarene-containing γ-nitroketones.

DOI Number:

10.1039/d4ra03826f

Reaction Category:

RXNO ID:

RXNO_0000009

Educt:

2-enoylazaarenes, nitromethane

Product:

(R)-4-nitro-3-phenyl-1-(pyridin-2-yl)butan-1-one

Catalyst:

3-[[3,5-bis(trifluoromethyl)phenyl]amino]-4-[[(8α,9S)-6′-methoxycinchonan-9-yl]amino]-3-Cyclobutene-1,2-dione

Cas No:

1256245-84-7

Cas No:

130-95-0