Organocatalytic atropo- and E/Z-selective Michael addition reaction of ynones with α-amido sulfones as sulfone-type nucleophile.

DOI Number:

10.1039/C8QO01241E
Link to literature

Reaction Category:

Atropisomer synthesis | Michael | Michael Addition

RXNO ID:

RXNO_0000009

Educt:

ynones, α-amido sulfones

Product:

axially chiral styrenes

Catalyst:

(2S)-2-[[2-[[3,5-bis(trifluoromethyl)phenyl]amino]-4,5-dioxo-1-cyclobuten-1-yl]amino]-N-[(9S)-6′-methoxycinchonan-9-yl]-3-methyl-butanamide

Cas No:

1648788-77-5

Associated Product from Buchler GmbH:

Quinine Base

Cas No:

130-95-0