Catalytic enantioselective hydrophosphinylation of in situ-generated indole-derived vinylogous imines to access 3-(1-diphenylphosphoryl-arylmethyl) indoles.
DOI Number:
10.1039/d2cc04763b
Reaction Category:
Educt:
2-methyl-3-(phenyl(tosyl)methyl)-1H-indole, bis(4-(trifluoromethyl)phenyl)phosphine oxide
Product:
(S)-((2-methyl-1H-indol-3-yl)(phenyl)methyl)bis(4-(trifluoromethyl)phenyl)phosphine oxide
Catalyst:
N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea
Cas No:
852913-16-7
Associated Product from Buchler GmbH:
Quinine Base
Cas No:
130-95-0