Antiviral bioactivity of chiral β-amino acid ester derivatives synthesized through a one-pot, solvent-free asymmetric Mannich reaction.

DOI Number:

10.1055/s-0037-1609910

Reaction Category:

RXNO ID:

RXNO_0000032

Educt:

4-methyl-6-(piperidin-1-yl)pyrimidin-2-amine, malonates, aldehydes

Product:

2-(((4-methyl-6-(piperidin-1-yl)pyrimidin-2-yl)amino)methyl)malonates

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7

Associated Product from Buchler GmbH:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8α,9S)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-16-7