Quinidine thiourea‐catalyzed aldol reaction of unactivated ketones: highly enantioselective synthesis of 3‐alkyl‐3‐hydroxyindolin‐2‐ones.

DOI Number:

10.1002/anie.201004161
Link to literature

Reaction Category:

Aldol | Aldol

RXNO ID:

RXNO_0000016

Educt:

substituted indoline-2,3-dione, methylketones

Product:

3‐alkyl‐3‐hydroxyindolin‐2‐ones

Catalyst:

N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(9R)-6′-methoxycinchonan-9-yl]thiourea

Cas No:

852913-25-8

Associated Product from Buchler GmbH:

Quinidine Base

Cas No:

56-54-2