Elucidation of the active conformation of cinchona alkaloid catalyst and chemical mechanism of alcoholysis of meso anhydrides.

DOI Number:

10.1073/pnas.1004439107

Reaction Category:

Educt:

(3aR,7aS)-hexahydroisobenzofuran-1,3-dione, 2,2,2-trifluoroethan-1-ol

Product:

(1R,2S)-2-((2,2,2-trifluoroethoxy)carbonyl)cyclohexane-1-carboxylic acid

Catalyst:

2-[[(9S)-6′-methoxycinchonan-9-yl]oxy]-acetic acid (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester

Cas No:

811811-41-3

Cas No:

56-54-2