Catalytic enantioselective synthesis of carboxy-substituted 2-isoxazolines by cascade oxa-Michael-cyclization.

DOI Number:

10.1039/C7OB02722B

Reaction Category:

MOP ID:

MOP_0000561

Educt:

2,4-disubstituted tert-butyl (Z)-4-oxobut-2-enoate, hydroxylamine

Product:

carboxy-substituted 2-isoxazolines

Catalyst:

(1S,2R,4S,5R)-1-(2,5-bis(trifluoromethyl)benzyl)-2-((S)-hydroxy(6-methoxyquinolin-4-yl)methyl)-5-vinylquinuclidin-1-ium bromide

Cas No:

Cas No:

56-54-2